منابع مشابه
Milestones in Nephrology
Being the last survivor a of the original triumvirate that launched the hairpin countercurrent theory of urine concentration, I thought it might be seemly for me to reminisce about how it came about 50 years ago. In 1946, I graduated in chemistry at the University in Budapest (Hungary) and became the lucky recipient of a fellowship offered by the University of Basel (Switzerland). A few months ...
متن کاملMilestones in lymphangioleiomyomatosis research.
L ymphangioleiomyomatosis (LAM), a slowly progressive disease affecting mostly young and middle-aged females [1], is one of the few orphan lung diseases that has attracted major attention in recent years from both clinicians and researchers [2], with rapidly evolving progress. With an estimated prevalence of one in 400,000 adult females aged 20–69 yrs for the sporadic form [3] and ,30% of patie...
متن کاملMilestones in ataxia.
The past 25 years have seen enormous progress in the deciphering of the genetic and molecular basis of ataxias, resulting in improved understanding of their pathogenesis. The most significant milestones during this period were the cloning of the genes associated with the common spinocerebellar ataxias, ataxia telangiectasia, and Friedreich ataxia. To date, the causative mutations of more than 3...
متن کاملMilestones in huntington disease.
There have been extraordinary advances in our knowledge of the underlying gene, the protein it encodes, various models of disease, and potential targets for effective therapies for Huntington disease. Huntington disease research has increased exponentially in the past 25 years, and we now understand many of the molecular mechanisms underlying the disease. Still, more work needs to be done befor...
متن کاملTemporal Milestones in HTNs
We present temporal milestones for hierarchical task networks to enable the complex synchronization of tasks. A temporal milestone of a task is an intermediate event that occurs during the execution of a complex task, e.g., the start time, the end time or a milestone of any of its subtasks. Unlike landmark variables, introduced in existing work, temporal milestones respect the task abstraction ...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2011
ISSN: 0022-202X
DOI: 10.1038/skinbio.2011.1